What's up with him? He looks furious.

　　他怎么了？他看上去怒氣沖沖。

　　What's up with you, chuck?

　　你怎么了，親愛的？

　　Hey, dude, what's up?

　　喂，哥們兒，怎么啦？

　　Let's sit down and then you can say what's up.

　　咱們先坐下來，然后你把事情告訴我。

　　What's that villain up to now?

　　這個壞家伙又在搞什么名堂？